The best podcasts for entrepreneurs building with AI are Built This Week, No Priors, Lenny's Podcast, My First Million, Training Data, Acquired, The a16z Show, All-In and Indie Hackers. They range from investors interviewing AI founders to tactical product advice, business-idea brainstorms and multi-hour company histories, so pick by what you need this quarter.
Built This Week is our show, so we put it first; here's how we picked the rest.
Built This Week is hosted by Jordan Metzner and Sam Nadler, co-founders of Ryz Labs, and has published weekly since June 2025, 53 episodes so far. Each episode we build something with AI on air, test new AI tools, interview a founder or operator, and cover the AI news, in about 21-28 minutes. It is for founders who want to see what they could build themselves this week, from internal tools to prototypes.
For example, Jordan built the Ryz Labs Autoblogger to publish posts across our brands' sites, and we built a solopreneur finance dashboard for our conversation with Collective CEO Hooman Radfar.
Start with: Episode 52: She Sold Her First AI Company to Google in 2009 (September 2026), with Rising Team founder Jennifer Dulski. See all episodes.
Investors Sarah Guo and Elad Gil host No Priors, produced by Conviction. Each week they interview leading AI engineers, researchers and founders about AGI timelines, market disruption and state-of-the-art research, in episodes of about 36-45 minutes. For founders it is a compact weekly read on where AI companies and research are going.
Start with: Andrej Karpathy on Code Agents, AutoResearch, and the Loopy Era of AI (March 2026). Read our full profile of No Priors.
Lenny Rachitsky interviews product, growth and AI leaders every week, aiming for concrete, tactical advice on building, launching and growing products. Recent guests come heavily from AI labs and AI-native companies, and episodes typically run 80-97 minutes. It is especially useful for founders who own product and growth themselves; it is rated 4.9 out of 5 from 1.4K ratings on Apple Podcasts, as of October 2026.
Start with: OpenAI’s Head of ChatGPT: We’re entering a new era of AI (again) | Tibo Sottiaux (October 2026). Read our full profile of Lenny's Podcast.
Sam Parr and Shaan Puri brainstorm business ideas based on market trends and opportunities, sometimes with guests, two to three times a week. AI tools and AI businesses are frequent topics. It is produced by HubSpot Media, episodes typically run 51-69 minutes, and it suits entrepreneurs and side-project builders hunting for their next idea. It is rated 4.7 out of 5 from 2.6K ratings on Apple Podcasts, as of October 2026.
Start with: How to Scale a Profitable Agency with 0 Employees (Using AI Agents) (June 2025). Read our full profile of My First Million.
Training Data is Sequoia Capital's podcast, hosted by Sonya Huang, Pat Grady and other Sequoia partners since 2024. They talk with leading AI builders and researchers about how AI technologies are evolving and what that means for business and society. Episodes run about 35-52 minutes, roughly weekly, and it suits founders who want to hear how top AI companies are being built.
Start with: Anthropic's Boris Cherny: Coding's Printing Press Moment (May 2026). Read our full profile of Training Data.
Ben Gilbert and David Rosenthal tell the full story and strategy of single companies, such as NVIDIA, Google and Microsoft, in long narrative deep dives, plus occasional interviews. Recently that has meant about one long episode a month, typically 169-256 minutes. For founders, it is a detailed look at how companies, including the ones that shaped AI, were built; it is rated 4.7 out of 5 from 5.4K ratings on Apple Podcasts, as of October 2026.
Start with: Google Part III: The AI Company (October 2025). Read our full profile of Acquired.
The a16z Show (long known as the a16z Podcast) is Andreessen Horowitz's flagship show on tech and culture trends, with rotating a16z partners, industry experts and business leaders. It publishes multiple episodes a week, typically 40-55 minutes, and AI is a major recurring topic. Founders and investors get a venture-capital view on AI and technology.
Start with: Inside Cursor: The Anatomy of a Generational Startup (August 2026). Read our full profile of The a16z Show (a16z Podcast).
Chamath Palihapitiya, Jason Calacanis, David Sacks and David Friedberg discuss current events, markets, technology including AI, and policy in a weekly main episode, plus frequent interviews from the All-In Summit and other events. Episodes typically run 37-90 minutes. It suits founders and investors who want a weekly markets, tech and politics roundup from a VC panel; it is rated 4.0 out of 5 from 10.4K ratings on Apple Podcasts, as of October 2026.
Start with: Satya Nadella on the AI Doomer Slowdown, Microsoft's Master Plan & Who Wins AI (September 2026). Read our full profile of All-In.
Courtland Allen and Channing Allen interview founders turning ideas and side projects into profitable online businesses, covering strategies and tools for bootstrapped companies. Episodes typically run 50-61 minutes. The most recent episode in the public feed is from June 2023, so treat it as a back catalog for bootstrapped founders and solo builders; it is rated 4.9 out of 5 from 493 ratings on Apple Podcasts, as of October 2026.
Start with: #281 – Seth Godin on Indie Hacking, Doing Hard Things, and Finding Significance in a Changing World (May 2023). Read our full profile of Indie Hackers.
Running a company rather than starting one? See the best AI podcasts for business, or the broader list of the best startup podcasts.
For AI-focused founders, No Priors, Lenny's Podcast, Training Data and My First Million cover building and growing companies, Acquired tells long company histories, and Built This Week shows AI tools used on real projects each week.
No Priors (Sarah Guo and Elad Gil, produced by Conviction) and Training Data (Sequoia Capital) both interview leading AI builders and researchers. The a16z Show and All-In bring investor perspectives on AI and technology.
Indie Hackers, hosted by Courtland and Channing Allen, interviews founders turning side projects into profitable online businesses. The most recent episode in its public feed is from June 2023, so treat it as an archive. My First Million is an active alternative focused on business ideas.
Built This Week. Jordan Metzner and Sam Nadler build something with AI on air every week, test new AI tools and interview a founder or operator.
